J Orthop Res 16 : 618621 Fenwick SA et al
High-risk features at baseline: Prior symptomatic gallstones or biliary colic Existing asymptomatic stones on prior imaging Obesity (BMI 35), particularly in female patients over 40 Rapid prior weight loss history Crohn's disease or terminal ileal resection (impairs bile salt reabsorption) Family history of cholelithiasis Patients with prior symptomatic gallstones should discuss prophylactic cholecystectomy with a surgeon before starting semaglutide, or at minimum have a baseline ultrasound documented in the chart
The administration negotiated how much both the government and consumers would pay for the drugs, which are used to treat obesity and diabetes as well as other cardiometabolic conditions
Previous Weight Loss Attempts Many providers consider your history of weight loss attempts when evaluating eligibility
"This is particularly concerning given that people with obesity-related comorbidities may reap the greatest benefit from treatment," said Professor Thomsen
FDA has stated that compounded GLP-1 products are not FDA-approved finished products and has continued enforcement activity against misleading promotion of non-FDA-approved compounded versions as though they were the same as FDA-approved drugs
